Human Thrombocytopenia Is Associated With Structural Abnormalities of the Endothelium
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چکیده
Capillary fragility is characteristic of severe thrombocytopenia. This mechanical weakness may not be solely accounted for by decreased ability of platelets to repair endothelial breaks. Platelets may have a role in maintaining endothelial hemeostasis. This laboratory has demonstrated thinnning of capillary endothelium in experimental thrombocytopenia. We now report similar findings in human thrombocytopenia. Capillary endothelium supplying either skin or skeletal muscle was found to have a mean thickness only half that of normal as well as frequent very
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تاریخ انتشار 2005